Clinical pulmonary infection score and procalcitonin for assessing the severity and prognosis of elderly patients with severe community acquired pneumonia

Abstract

Objective To investigate the value of clinical pulmonary infection score (CPIS) and procalcitonin (PCT) in the treatment of elderly patients with severe community-acquired pneumonia (SCAP). Methods Total of 60 elderly patients with SCAP in our hospital from February 2014 to February 2016 were collected. According to the prognosis, the patients were divided into survival group and death group. The difference of PCT, white blood cell (WBC), CPIS score between the two groups at the first day and 7th day after hospital admission were detected and their correlations with CPIS were analyzed. Results Compared with the first day, the levels of PCT and CPIS in the survival group were not significantly decreased at the 7th day after hospital admission (P all 0.05). Compared with the first day, the levels of WBC, PCT and CPIS in the death group were not significantly changed (P all > 0.05). After 7 days treatment, there were significant difference in PCT and CPIS between the two groups (P all 0.05). After 7 days treatment, WBC was not associated with prognosis (P > 0.05), and PCT and CPIS were significantly correlated with the prognosis of SCAP (r = 0.44, P = 0.023; r = 0.58, P = 0.017). Conclusions PCT and CPIS were associated with severity and prognosis in elderly patients with SCAP in elderly patients. It could be used as a good biomarker for evaluating the prognosis of SCAP, which could be used for further treatment. Key words: Clinical pulmonary injection score; Arocalcitonin; Severe community acquired pneumonia; White blood cell