Abstract

OBJECTIVE: Tamoxifen is commonly used for the adjuvant treatment after chemotherapy or metastatic disease in women with hormone receptor-positive breast cancer. Clinical profiles during tamoxifen therapy have not been evaluated in patients who took GnRH agonist injection for ovarian protection. Therefore, this study was conducted to evaluate menstrual patterns, hormonal profiles and endometrial effects in tamoxifen-treated premenopausal breast cancer patients.

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