Clinical Profile of Patients with Hyperthyroidism in Zagazig University Hospitals

Abstract

Hyperthyroidism is a condition that occurs due to over production of thyroid hormones by the thyroid gland . It can be categorized according to thyroid hormone levels into overt and subclinical hyperthyroidism. Also could be classified into, normal (or high) and low thyroid radioactive iodine uptake according to radioiodine uptake. So, the aim of this study was to evaluate the difference in the clinical profile between hyperthyroid patients and its relation to thyroid scan imaging. Also to avoid prescribing antithyroid medications to patients with thyroiditis, this could lead to hypothyroidism . Materials and methods: This is a prospective cohort study for patients with hyperthyroidism. Patients have been enrolled from Endocrinology Outpatient Clinic at Zagazig University Hospitals in the period from December 2018 to October 2020. Results: patients were divided into two major groups, overt hyperthyroidism (group 1) and subclinical hyperthyroidism (group 2). All patients of group (1) had abnormal thyroid gland examination but, only 50 % of group (2) patients had showed abnormal gland examination (p= <0.001). 83 .3% of patients of group (1) had high thyroid uptake and 62.5 % of patients of group (2) had high thyroid uptake (p=0.108). There was highly statistical significance between the two groups as regard F. T4( P = <0.001) and F .T3 (p = < 0.001 ) , but no difference in TSH( p =0.223) . Conclusion: The thyroid scan had cross linkage with abnormal thyroid function ,