Abstract

Clinical Profile of Non-Motor Symptoms in Patients with Essential Tremor: Impact on Quality of Life and Age-Related Differences

Highlights

  • Essential tremor (ET) is one of the most common tremor disorders, which is characterized mainly by the presence of action tremor of the hands

  • Patients with essential tremor (ET) were subjected to comprehensive history, including medical comorbidities, and examination, and they were evaluated by Fahn Tolosa Marin Tremor Rating Scale (FTMRS) for tremor severity; Non-Motor Symptoms Scale (NMSS) for NMSs11; the Montreal Cognitive Assessment (MoCA) – Arabic version for cognitive f­unctions12; Beck Depression Inventory (BDI) for depression13; Hamilton Anxiety Rating Scale (HARS) for anxiety14; Pittsburgh Sleep Quality Index (PSQI) for sleep problems15; and the Arabic version of Short Form 36 Health Status Questionnaire (SF-36) for quality of life (QoL).16

  • The current study explored several NMSs associated with ET and detected their negative impact on QoL

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Summary

Introduction

Essential tremor (ET) is one of the most common tremor disorders, which is characterized mainly by the presence of action tremor of the hands. Identifying the clinical phenotypes of non-motor symptoms (NMSs) of essential tremor (ET) among different populations is necessary due to their impact on the quality of life (QoL). Subjects were evaluated by the Fahn-Tolosa-Marin Tremor Rating Scale, Non-Motor Symptoms Scale (NMSS), Montreal Cognitive Assessment, Hamilton Anxiety Rating Scale, Beck Depression Inventory, Pittsburgh Sleep quality Index, and the Short Form 36 Health Survey Questionnaire. Both groups were divided into two subgroups of younger (45 years, 16 patients) groups, to investigate age-related differences. NMSs should be explored for proper care of ET patients

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