Clinical Profile of Multidrug-Resistant Organisms at Burn Center Dr. Soetomo General Hospital Surabaya from June 2020 to June 2021

Abstract

Background: Burns are an ideal environment for primary wound infection to occur. Burn infection can lead to the acquisition of Multidrug-Resistant Organisms (MDRO) with certain risk factors, such as the cause, degree and total body surface area (TBSA) of burns, length of stay, and invasive procedures performed. This study aims to determine the clinical profile of burn patients who experience MDRO. Method: Data was taken using medical records at the Burn Center Dr. Soetomo General Hospital Surabaya during June 2020 – June 2021 with a descriptive study and a cross sectional approach. Result: A total of 67 burn patients were included in this study. Sixteen patients were found to have burns with MDRO, and 51 other patients only had burns without MDRO which was excluded in this study. Patient in this study were dominated by men with a total of 11 patients (68.8%), most patient were in the 19–45-year age group of 8 patients (50%) with an average of 35 ± 20.58 years, and length of stay >14 days in 11 patients (68.8%) with an average 32,75 ± 38.31 days. All patients had invasive procedures performed. Fire was the most common cause of burns, namely in 9 patients (56.3%). Severe burns occurred in 16 patients (100%) of the MDRO burns studied. Eleven patients (68.8%) had TBSA > 30% with an average of 37.06% ± 18.59%. Acinetobacter baumannii was the most MDR bacteria cultured in this study with 15 cultures (32.6%). It is followed by Pseudomonas aeruginosa with 9 cultures (19.6%) and Klebsiella pneumoniae with 4 cultures (8.7%). A. baumannii is most commonly found in blood cultures, followed by cultures of phlegm and wounds. This is in contrast to P. aeruginosa with the most findings in wound cultures, followed by cultures of sputum and blood. Conclusion: Our study shows that MDRO infection is still a matter of concern in burns. Even so, the number of samples should be increased to see the significance and the relationship between variables in future burn studies.