Clinical profile of dengue infection in pregnancy – A hospital-based study

Abstract

Abstract Background Dengue is a major public health problem. The present study aimed to determine clinical profile of pregnant patients suffering from dengue. Methodology An observational study was conducted in the Obstetrics department of a tertiary care centre of Delhi, over 10 weeks (July to mid-September 2016). Pregnant patients suffering from dengue were included. Data was collected with basic demographic profile, historical details, investigations including platelet counts and maternal consequences. Results One hundred and twenty pregnant patients were admitted with fever, of which 25 (20.8%) had dengue. Eleven (44%) of these pregnant women were in 20–25 years age group, and 9 (36%) were in 25–30 years age group. Fever ( n = 22, 88%) and myalgia ( n = 20, 80%) were the most common presenting symptoms. Eighteen (72%) patients presented in third trimester. Thrombocytopenia was present in 60% cases. 12% dengue patients required platelet transfusion. 20% went into preterm labour and 8% had dengue haemorrhagic fever. Conclusion Fever and myalgias are the most common presenting symptoms of dengue in pregnancy. Dengue fever in pregnancy most often is treated conservatively. Preterm labour is a common complication in patients presenting in third trimester. Prompt diagnosis of pregnant women with dengue infection is necessary for effective management and better feto-maternal outcome.