Abstract
ABSTRACT Background: Population aging and mobility have increased the exposure of elderly individuals to dengue. This study evaluated the clinical features of dengue in the elderly during the epidemic (2008 and 2012) and interepidemic (2009 and 2010) periods. Methods: This cross-sectional study was based on dengue surveillance data from Rio de Janeiro, Brazil: 2008 (n=31,210), 2009‒2010 (n=2,884), and 2012 (n=30,773). The analysis was stratified by age group (<60 and ≥60 years). Results: Case-fatality rates were higher in the elderly. In 2008, elderly individuals were found to be more prone to hematuria and thrombocytopenia. Conclusions: These results can improve the understanding of dengue in elderly individuals who live in or travel to tropical regions.
Highlights
Population aging and mobility have increased the exposure of elderly individuals to dengue
Population aging has led to an increase in the proportion of elderly residents in tropical areas, increasing their vulnerability to dengue infection
The elderly are frailer and more prone to developing complications from diseases, which can be associated with physiological factors, immune alterations, comorbidities, or external factors, such as environmental conditions in the place of residence
Summary
Population aging and mobility have increased the exposure of elderly individuals to dengue. The current study aimed to assess the clinical features of dengue in the elderly in two epidemics in the city of Rio de Janeiro in 2008 and 2012, when the main circulating serotypes were DENV-2 and DENV-4, respectively. This study included dengue cases reported to SINAN in the resident population of the city of Rio de Janeiro.
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