Abstract
Introduction: Critical Care management is an important issue in developing countries where Medical Intensive Care Units (MICU) patients have comorbidity or complications of multisystem involvement.
 Objectives: The objective of study was to analyze clinical profiles of patients in Medical Intensive Care Unit and identify applicable factors that prognosticate outcomes.
 Methodology: Study conducted at Medical Intensive Care Unit of B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Records from July 31, 2013 to August 1, 2014 were retrospectively studied. Clinical profiles were analyzed, outcomes defined as improved, referred, Leave Against Medical Advice (LAMA) or death. An online calculator (MD+Calc) was used to calculate Sequential Organ Failure Assessment Score (SOFA). Descriptive statistics were used, values <0.05 were statistically significant.
 Results: Of 70 patients 36 (51.4%) were female, 30 (42.9%) had sepsis of which 12 (40%) had Community-Acquired Pneumonia. 8 (11.43%) had Acute Respiratory Distress Syndrome, 7 (10%) had congestive cardiac failure. 43 (61.43%) improved, 17 (24.3%) expired, 9 (12.86%) LAMA, one patient was referred. Sequential Organ Failure Assessment Score was >9 in 23 (41.07%) cases. Of 17 expired cases, 14 (82.35%) had SOFA score >9.
 Conclusion: Sepsis with pulmonary involvement is primary diagnosis in patients requiring Medical Intensive Unit Care. Sequential Organ Failure Assessment Score was useful for prognostication and can be used for better clinical decision-making.
Highlights
Pa ents admi ed to Medical Intensive Care Unit may require management of mul system derangements and cri cal care
Majority of the pa ents belonged to the younger age group of ≤50 years (65.71%), and 17.14% were above 71 years
Mul disciplinary approach to care for cri cally ill pa ents in the intensive care unit was low
Summary
Pa ents admi ed to Medical Intensive Care Unit may require management of mul system derangements and cri cal care. The capital of Nepal, Kathmandu has 11 government hospitals, 8 community-based hospitals, and 32 private hospitals Of these 51 hospitals, 33 have intensive care facili es, with a total of 331 beds, of which only 161 beds have mechanical ven lators.[1] The Central Bureau of Sta s cs in Nepal in 2011 observed 15.2 beds per 100000 popula on, and 7.2 beds with ven lator facility per 100000 popula ons.[2] Data on profiles and outcomes of pa ents admi ed in intensive care units outside the capital city are few. Research on clinical characteris cs and outcomes of intensive care unit pa ents are an important tool for improving the standard of care
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