Abstract
BackgroundThe first government funded and sustainable dialysis unit was established in Ethiopia at Saint Paul’s Hospital Millennium Medical College (SPHMMC). This has led to the development of a unique cohort of patients about which very little is known. This study was conducted to describe the clinical profile and outcome of adult Acute Kidney Injury (AKI) patients treated with intermittent haemodialysis at the dialysis center of SPHMMC.MethodsA retrospective review of clinical records of cases of AKI who required haemodialysis support during the time period from August 1, 2013 to February 1, 2015 was conducted.ResultsA total of 151 cases AKI requiring dialysis were included for the study. Overall, the patients were generally younger with a mean age of 36.7 years and thus with few premorbid conditions. The most common causes of AKI were hypovolemia (22.5 %), acute glomerulonephritis (AGN) (21.9 %) and pregnancy related causes (18.5 %). Nearly a third (29.1 %) of patients succumbed to the AKI.ConclusionInfections, AGN, obstetric causes and nephrotoxins were the primary causes of dialysis requiring AKI. Most of these causes can be prevented with simple interventions such as health education on oral rehydration, quality prenatal and emergency obstetric care, appropriate management of infections and taking appropriate precautions when prescribing potentially nephrotoxic medications.
Highlights
The first government funded and sustainable dialysis unit was established in Ethiopia at Saint Paul’s Hospital Millennium Medical College (SPHMMC)
The aim of this study is to describe the clinical profile and outcome of all adult Acute Kidney Injury (AKI) patients treated with intermittent haemodialysis at the unit in the first 18 months since its establishment
The others were excluded because 10 were paediatric patients, 9 had haemodialysis for overdose of dialyzable drugs and the rest were dialyzed for Chronic Kidney Disease (CKD) or their records were missing
Summary
The first government funded and sustainable dialysis unit was established in Ethiopia at Saint Paul’s Hospital Millennium Medical College (SPHMMC). This has led to the development of a unique cohort of patients about which very little is known. This study was conducted to describe the clinical profile and outcome of adult Acute Kidney Injury (AKI) patients treated with intermittent haemodialysis at the dialysis center of SPHMMC. Whether occurring in the community or in the hospital, the clinical and public health importance of AKI is well established due to the association with high mortality and its separate independent effect on the risk of death and resource use [2].
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