Abstract
Accidental mushroom poisoning is constantly seen and regularly reported from all over world. Exact magnitude of problem and its clinical profile in Nepal is not well known. This study was done to evaluate clinical profile and treatment outcome of patients presenting with mushroom poisoning in the department of internal medicine, BPKIHS, Dharan. It is a prospective observational study conducted in department of internal medicine, BPKIHS, Dharan from 1st January 2008 to 31st December 2009. Informed consent was taken. All the patients were subjected to necessary laboratory investigation. They were followed up at 1 week and 1 month after discharge. All together 60 patients were analyzed. Majority of subjects 56 (93.3%) were from rural areas. Vomiting and diarrhea were the two most common presentations seen in 56 (93.3%) subjects. The latent period for the symptoms were >6 hours in 4 (6.7%) and <6 hours in 56 (93.3%) subjects. Fulminant hepatic failure was seen in 6 (10%) subjects and among them 4 (66.7%) expired. After admission 3 (5%) subjects developed GI bleeding. Average duration of hospital stay was 4.6 days. In follow up recovery was complete in all subjects who survived the acute phase of poisoning. Especially in patients coming during rainy season mushroom poisoning should be considered in the differential diagnosis of acute gastroenteritis. Mortality is high in subjects with FHF whereas recovery is complete in subjects who survived the acute phase.
Highlights
Accidental mushroom poisoning is constantly seen and regularly reported from all RYHU ZRUOG
All the suspected patients of mushroom poisoning presented in the department of internal medicine from 1st January 2008 to 31st December 2009 were included in the study
All together 60 patients came with mushroom poisoning during the study period were enrolled and analysed
Summary
Accidental mushroom poisoning is constantly seen and regularly reported from all RYHU ZRUOG Mushroom poisoning refers to deleterious effects resulting from ingestion of toxic substances present in a mushroom. Over 5000 varieties of mushrooms are present in the world, but only a 100 are toxic.[1] Utility values of Nepalese mushrooms has been tabulated by Adhikari are 110 as edible, 13 as medicinal, 45 as toxic and 6 others.[2] Accidental mushroom poisoning is constantly seen all over world. Claudius and Pope Clement VII are said to have been murdered by mushroom poisoning.[3]. According to mushroom poisoning registry of the North American Mycological Association incidence is JNMA I VOL 52 I NO. According to mushroom poisoning registry of the North American Mycological Association incidence is JNMA I VOL 52 I NO. 8 I ISSUE 192 I OCT-DEC, 2013
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