Abstract
Clinical profile and outcome of children with tuberculosis in a tertiary care hospital in Mumbai, India
Highlights
As children are usually infected by an adult with pulmonary tuberculosis (TB), childhood TB reflects transmission of Mycobacterium tuberculosis within a community all cases except the case of the Potts spine patient who had a residual spine deformity after completing treatment
Twenty (66.6%) children had a history of previous adult contact with TB, 29 (96.6%) were vaccinated with Bacillus Calmette Guerin (BCG) and 10 (33.3%) were malnourished
As children are usually infected by an adult with pulmonary tuberculosis (TB), childhood TB is a reflection of the transmission of Mycobacterium tuberculosis within a community[1,2,3]
Summary
As children are usually infected by an adult with pulmonary tuberculosis (TB), childhood TB reflects transmission of Mycobacterium tuberculosis within a community all cases except the case of the Potts spine patient who had a residual spine deformity after completing treatment. As children are usually infected by an adult with pulmonary tuberculosis (TB), childhood TB is a reflection of the transmission of Mycobacterium tuberculosis within a community[1,2,3]. Rise in the urban population with consequent overcrowding and migration of families from rural areas to cities for work have led to increased poverty, malnutrition, morbidity and mortality rate of several diseases including TB5. Poor immunisation coverage with BCG vaccine has been shown to play a significant role in the higher incidence and case fatality rate of neuro-TB12. The diagnosis of TB in childhood is most challenging as it is a pauci-bacillary disease relying on both clinical and radiological features for diagnosis and management[13]
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