Abstract
Reports about the radiologic features of minute pulmonary meningothelial-like nodules are sparse. This study aims to investigate the radiologic features of minute pulmonary meningothelial-like nodules. From January 2016 to April 2019, 7589 patients underwent pulmonary resections at Fudan University Shanghai Cancer Center. Postoperative pathology records were reviewed retrospectively. Fifty-nine patients with minute pulmonary meningothelial-like nodule were included. The identification of minute pulmonary meningothelial-like nodules in pathology specimen included pathologically confirmed in resected nodules, and discovery in the peripheral tissue of other resected nodules incidentally. We went back and checked all the pre-operative scans of patients to analyze surgical decision and observe any change of visible minute pulmonary meningothelial-like nodule over time. Clinic, radiologic and pathological features were collected. Fifty-nine patients included 10 men and 49 women, with a mean age of 57.7. Five patients had history, while 54 patients were non-smokers. 79min pulmonary meningothelial-like nodules was found. Of them, 36 nodules were not visible on computed tomography scan. 43 nodules were visible on computed tomography scan, with an average size of 5.3mm in 29 patients. Computed tomography appearance included pure ground-glass opacity in 36, mixed in 2, and solid nodules in 5. Nearly half of patients had a pre-operative follow-up more than 6months (13/29, 44.8%). The median pre-operative radiologic follow-up was 4.9months. Approximately 90% of patients underwent pulmonary surgery because of other malignant nodule on chest computed tomography scan (52/59, 88.1%). Most minute pulmonary meningothelial-like nodules tend to present as ground-glass opacity, especially pure ground-glass opacity. Continuous computed tomography monitoring revealed no radiologic change over time. Continuous computed tomography monitoring was necessary part of management of minute pulmonary meningothelial-like nodule.
Highlights
Minute pulmonary meningothelial-like nodules (MPMNs) are discovered identified in autopsy or resected lung specimens[1]
Most minute pulmonary meningothelial-like nodules tend to present as ground-glass opacity, especially pure ground-glass opacity
Main diagnosis was minute pulmonary meningothelial-like nodules in 14 patients, adenocarcinoma in 42 patients, atypical adenomatous hyperplasia in 2 and metastatic lung cancer in 1. 46 patients had single minute pulmonary meningothelial-like nodule, 13 patients had more than one nodules. 79 minute pulmonary meningothelial-like nodules was found
Summary
Minute pulmonary meningothelial-like nodules (MPMNs) are discovered identified in autopsy or resected lung specimens[1]. These benign pulmonary nodules are usually asymptomatic, which does not require surgical treatment. With the development and popularization of thin-section chest CT scan, some MPMNs can visible on chest CT scan and presented as simulate malignant nodules. Few studies had reported radiologic appearance of MPMNs. In this study, we included 59 cases of MPMNs, described their features and discussed their management
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
