Abstract
Ductal breast cancer is a clinically heterogeneous disease; we investigate the correlation between tumor size, comedo necrosis, number of cell mitoses and axillary lymph node metastasis in ductal breast cancer. In this study, 104 ductal breast cancer specimens were collected and divided into 3 groups: T1 group (tumor size ≤ 2 cm), T2 group (2 5.0 cm). Among those specimens, 95 cases were diagnosed with invasive ducted carcinoma, and 9 cases were ductal carcinoma in-situ (DCIS). Results show that T3 group has a higher rate of axillary lymph node metastasis than T2 group and T1 group; T2 group has a higher rate of lymph node metastasis than T1 group. The patients with the number of cell mitoses (≥10) were also has a higher rate of axillary lymph node metastasis (P = 0.0139) than the patients with the number of cell mitoses (
Highlights
Breast cancer is the most common malignant tumor among women, most of which are confirmed by pathological examination
Ductal breast cancer is a clinically heterogeneous disease; we investigate the correlation between tumor size, comedo necrosis, number of cell mitoses and axillary lymph node metastasis in ductal breast cancer
Results show that T3 group has a higher rate of axillary lymph node metastasis than T2 group and T1 group; T2 group has a higher rate of lymph node metastasis than T1 group
Summary
Breast cancer is the most common malignant tumor among women, most of which are confirmed by pathological examination. 104 cases of ductal breast cancer specimens were collected. Samples were retrieved from 104 ductal breast cancer patients, tissues were made into paraffin blocks and HE staining, diagnosed by pathological doctors. Pathological type: 9 cases of carcinoma in situ (Figure 1(a)), 95 cases of invasive ductal carcinoma (Figure 1(b))
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