Abstract
Clinical Overlapping in Autoinflammatory Diseases: The Role of Gene Duplication.
Highlights
Specialty section: This article was submitted to Inflammation, a section of the journal Frontiers in Immunology
Most cases of autoinflammatory diseases (AIDs) are characterized by attacks of systemic inflammation resulting in recurrent fever, acute arthritis, and increased acute phase proteins
The discovery of the first autoinflammatory gene, MEFV, responsible for familial Mediterranean fever has dramatically increased the understanding of the pathophysiology of AIDs, shedding light on the associated defective signaling pathways [1]
Summary
Specialty section: This article was submitted to Inflammation, a section of the journal Frontiers in Immunology. Clinical Overlapping in Autoinflammatory Diseases: The Role of Gene Duplication. Most cases of autoinflammatory diseases (AIDs) are characterized by attacks of systemic inflammation resulting in recurrent fever, acute arthritis, and increased acute phase proteins.
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