Abstract

The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. The journal also has a website. Free full text access is available for all readers.The Sri Lanka Journal of Child Health is now indexed in SciVerse Scopus (Source Record ID 19900193609), Index Medicus for South-East Asia Region (IMSEAR), CABI (Centre for Agriculture and Bioscience International Global Health Database), DOAJ and is available in Google, as well as Google Scholar.The policies of the journal are modelled on the Committee on Publication Ethics (COPE) Guidelines on Principles of Transparency and Best Practice in Scholarly Publishing. Sri Lanka Journal of Child Health is recognised by the International Committee of Medical Journal Editors (ICMJE) as a publication following the ICMJE Recommendations.

Highlights

  • Neonatal hypoxic respiratory failure affects 2% of all live births and is responsible for more than one third of all neonatal deaths[1]

  • Our study highlighted hyaline membrane disease (HMD) as the most common cause of pulmonary hypertension of the newborn (PPHN) in preterm neonates whereas meconium aspiration syndrome (MAS) was mostly found in term neonates

  • Persistent pulmonary hypertension of the newborn (PPHN) is a clinical syndrome during the early neonatal period characterized by severe arterial hypoxaemia caused by increased pulmonary vascular resistance with resultant shunting through fetal channel

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Summary

Introduction

Neonatal hypoxic respiratory failure affects 2% of all live births and is responsible for more than one third of all neonatal deaths[1]. Incidence is 1.8 to 2 per 1000 live births[2,3] and it is likely to be higher in developing countries[4,5]. It affects 2% of preterm neonates who develop hyaline membrane disease (HMD)[6]. Persistent pulmonary hypertension of the newborn (PPHN) is a clinical syndrome during the early neonatal period characterized by severe arterial hypoxaemia caused by increased pulmonary vascular resistance with resultant shunting through fetal channel (at the atrial and ductal level). Persistent pulmonary hypertension of the newborn (PPHN) is characterized by severe arterial hypoxaemia caused by increased pulmonary vascular resistance with resultant shunting through fetal channel (at the atrial and ductal level).

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