Abstract
Objective To compare the clinical outcome of intramedullary nail with locking plate in the treatment of two-part proximal humerus fractures. Methods PubMed, SpringerLink, EMBASE, The Cochrane Library, Medline, Science Direct, CNKI, Wanfang Data and VIP database were searched for relevant studies comparing intramedullary nailing and locking plate fixation of two-part proximal humerus fractures. A meta-analysis of the two methods was conducted using the RevMan 5.0. Differences between the two methods were compared with respect to operation time, intraoperative bleeding, bone union time, Constant score and postoperative complication incidence. Results Seven studies were included in the meta-analysis, with 136 patients treated with intramedullary nail and 159 patients treated with locking plate. Intramedullary nailing showed advantages over locking plate fixation with regards to operation time (WMD=-27.71, 95%CI-36.07--19.35, P 0.05) and postoperative complication incidence (OR=0.89, 95%CI 0.43-1.84, P>0.05). Conclusion Intramedullary nail is superior to locking plate in operation time, intraoperative blood loss and bone union time for the treatment of two-part proximal humerus fractures, but the two methods are similar in Constant score and postoperative complications rate. Key words: Fracture fixation, intramedullary; Bone plates; Humeral fractures; Meta-analysis
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