Clinical ocular region manifestations of 167 cases with human immunodeficiency virus infection

Abstract

Objective To analyze the pathological characteristics of ocular region in patients with human immunodeficiency virus (HIV) infection in order to detect and treat early to reduce the damage of visual function. Methods Retrospective analyzed 167 cases of HIV infection of their ocular region pathology,course of disease,symptoms,signs and general condition in three hospitals from November 2006 to November 2008 in Republic of Niger.Results A total of 167 patients were included in this study.Among them,33 cases with eye lesions appeared first (19.76％),ocular region pathology manifested as opportunistic infection and sarcoma formation,86 cases (51.0％) as amphiblestritis,46 cases as uveitis (28.0％),32 cases as zona (19.0％),19 cases as nerve system lesions (11.0％),15 cases as Kaposi sarcoma (9.0％).Impairment of vision below normal was seen in 98 cases (including 17 cases of severe bilateral blindness,mild in 19 cases,mild single-blind 34 cases),normal 69 cases.All patients with symptoms of varying degrees all over consumptions,CD4/CD8 ratio decreased in 146 patients,averaged 0.056 (normal 1.75-2.10). Conclusions HIV infection with eye lesions occurs in 40-92.3％.Impairment of vision is mainly caused by amphiblestritis and uveitis.In view of increasing HIV infection,ophthalmologist should pay more attention to its early ocular symptoms and sign and offer early treatment to improve the quality of life for patients. Key words: HIV infection; Eye symptom; Sign; Retrospective analysis