Abstract
Forty-one patients in the Peoples Republic of China were poisoned by ethyl mercury chloride, caused by the ingestion of rice that had been treated with the chemical. A dose-response relationship was found. Five months after the onset of the intoxication, the patients were still in poor condition. They were treated with two chelating agents, sodium dimercaptopropane sulfonate (DMPS) and sodium dimercaptosuccinate (DMS), whose effects were compared. Both agents were effective but DMPS was superior. Although urinary excretion is not the best estimate of body burden in alkyl mercury intoxication, during chelation therapy urinary mercury was an effective indicator for diagnosis and assessment of the degree of intoxication. Chelation therapy was diagnosis and assessment of the degree of intoxication. Chelation therapy was useful as long as the urinary mercury level was elevated.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
