Abstract
Objective To study the clinical effect of treating acute exacerbation of chronic respiratory failure with Danhong injection.Methods According to random number table,64 cases of acute exacerbation of chronic respiratory failure were divided randomly into 2 groups,with 32 cases in each group.Both groups were given correspondingly conventional symptomatic treatment (including oxygen,anti-inflammatory,antispasmodic,sputum,etc.).On this basis,the treatment group was added Danhong injection 30 ml+5％glucose infusion 250 ml,once a day,continuous therapy for 14 days.Results The total effective rate was 87.50％ and 65.63％ in Danhong injection treatment group and conventional treatment group respectively,showing obvious difference between 2 groups (x2=4.267,P＜0.05).The blood low shear viscosity (7.11 ± 1.60) mPa ? s,high shear viscosity of whole blood (3.30 ± 0.83 ) mPa ? s,plasma viscosity ( 1.28 ± 0.32) mPa ? s,whole blood reduced viscosity ( 16.81 ± 3.32 ) mPa ? s,erythrocyte aggregation index ( 1.26±0.31 ),erythrocyte deformation index (0.64±0.27) in the Danhong injection treatment group all had statistical significance compared to the conventional treatment group(P＜0.05).Conclusion Clinical efficacy and safety of Danhong injection in treating acute exacerbation of chronic respiratory failure were good. Key words: Chronic respiratory failure; Danhong injection; Hemorrheologic
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