Abstract

Objective To investigate the protective effects of compound E-Jiao oral liquid on peripheral blood of patients treated with chemotherapy.Methods 163 patients of malignant tumors were selected.All patients were randomly recruited into a treatment group and a control group.The control group was administered with chemotherapy alone,while the treatment group was additionally treated with compound E-jiao oral liquid twice a day and 40 ml each time.Peripheral hemogram,KPS score and questionnaire of life quality were observed at the day before chemotherapy,and the first day,seventh days after chemotherapy and the day before the second cycle of chemotherapy.Results At the first and the seventh day after chemotherapy,the white blood cell count [the value was (5.315±1.401) × 109/L,(5.011±1.541) × 109/L in the treatment group respectively; and (4.621 ± 1.012) × 109/L,(4.127± 1.061) × 109/L in the control group respectively],KPS score [the value was (70.513±8.217),(85.000±7.168) in the treatment group respectively; and (65.147±7.102),(70.198±9.511) in the control group respectively]and quality of life [the value was (69.781 ±8.217),(80.000±7.521) in the treatment group respectively and (64.911±7.412),(68.011±8.542) in the control group respectively] showed significant differences (P＜0.05).At the day before the second cycle of chemotherapy,two groups showed significant differences in the white blood cell count,hemoglobin,platelet count,KPS score and quality of life [the values were (5.584±1.591)× 109/L,(118.891±14.213)g/L,(212.097± 114.769) × 109/L,(88.641±3.019),and (79.541 ±3.121) in the treatment group respectively; the values were (3.937± 1.013) × 109/L,(99.143± 11.351) g/L,(180.219±61.643) × 109/L,(75.463±9.871),and (72.219±7.462) in the control group respectively] (P＜0.05).Conclusion Compound E-Jiao oral liquid has a protective effect on peripheral hemogram of patients treated with chemotherapy,besides its significantly improving the life quality of these patients. Key words: Compound E-Jiao oral liquid; Chemotherapy; Peripheral hemogram; Quality of life

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