Abstract

Objective To compare the efficacy and adverse effects of radiotherapy currently combined with different chemotherapy for local advanced non-small cell lung cancer (NSCLC). Methods Sixty-five patients with NSCLC were divided into two groups. Group A was given taxol and cisplatin, and group B was given taxol and cisplatin combined with radiotherapy. The two groups were compared on the efficacy and safety. Results The total response (CR+PR) were 36.7% (group A) , 65.7% (group B),X2=10.581, P<0.05. The 1 year survival rates of group A were 30.0% and 54.3% of group B,X2=9.339, P<0.05. The adverse effects showed no significant difference (X2 value was 2.011, 0.007, 2.206 respectively, P0.05). Conclusion The radiotherapy concurrently combined with taxol and cisplatin chemotherapy for patients with NSCLC could be more effectively, and the patients could tolerate the side effects, this therapy method was secure and receivable. Key words: Carcinoma, non-small cell lung; Drug therapy, combination; Radiotherapy

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