Clinical observation of modified trabecnlectomy with mitomycin C for the treatment of glaucoma

Abstract

Objective To explore the clinical efficiency of modified trabeculectomy with mitomycin C (MMC) on glaucoma.Methods 42 cases(64 eyes) with glaucoma received the modified trabeculectomy,0.4 mg/ml MMC was used in the operation.The clinical efficiency and complication were conducted.The post-operative follow-up periods ranged from 6 to 12 months.Results At 1 month,the visual acuity in 58 eyes (90.6％) increased in different le-vels,at 1 week,the IOP of all patients decreased in different levels and,48 eyes(75.0％ ) were lower than 21mmHg.At 6 months,the IOP were lower than 21 mm Hg in 54eyes (84.4％),there were diffused and flat functioning blebs in 56 eyes(87.5％ ) and non-functioning blebs in 8 eyes (12.5％).58 eyes (90.6％)had successful operations:54 eyes (84.4％) without medicine and 4 eyes( 6.3％ ) with medicine,6 eyes(9.4％ ) failed.The postoperative complications were comeal edema (5 eyes) and anterior chamber fibrin exudation(4 eyes).Conclusion Modified trabeculectomy with mitomycin C for glaucoma can effectively reduce postoperative scar adhesion of the filtration passage and lower the IOP to a target level.It is a safe and effective treatment for glaucoma,which needs no special equipments but shorter time,fewer complications and light damage. Key words: Glaucoma; Trabeculectomy,modified; Mitomycin C