Clinical observation of Fuzheng-Shugan decoction on treating thyroid nodule

Abstract

Objective To investigate the clinical effect of Fuzheng-Shugan decoction on the treatment of patients with the treatment nodule. Methods A total of 80 patients with thyroid nodule from Jan.2014 to Dec.2015, divided into two groups. The efficacy, thyroid stimulating hormone, high risk factors, the maximum diameter and volume of thyroid nodules were observed. Results The effective rate of observation group was significantly higher than of the control group(90.00% vs. 27.50%, χ2=32.237, P=0.000). The shortness of breath(1.62 ± 0.86 vs. 4.35 ± 1.13, t=12.159), foreign body sensation(2.53 ± 0.62 vs. 4.23 ± 0.56, t=12.289), irritability(1.56 ± 0.53 vs. 3.52 ± 1.25, t=9.130), sweating(1.85 ± 0.62 vs. 4.23 ± 0.56, t=18.017), tongue(1.58 ± 0.93 vs. 3.71 ± 1.25, t=8.646)and neck pain(0.82 ± 0.35 vs. 3.92 ± 0.65, t=26.558)in the obversation group were significantly lower than those in the control group(P<0.05). The thyroid stimulating hormone levels in the observation group(1.05 ± 0.21 mIU/L vs. 2.16 ± 0.71 mIU/L, t=9.482), were significantly lower(P<0.05). The maximum diameter(8.52 ± 4.72 mm vs. 12.27 ± 5.69 mm, t=3.208)nodule volume(0.26 ± 0.71 cm3vs. 0.96 ± 1.02 cm3, t=3.562)and high risk factors(2.73 ± 1.45 vs. 4.05 ± 1.36, t=4.199)in the observation group were significantly lower than those in the control group(P<0.05). Conclusion The Fuzheng-Shugan decoction can improve TCM syndrome, reduce the risk factors, and effectively reduce the nodule maximum diameter and volume. Key words: Thyroid nodule; Fuzheng-Shugan decoction; Thyroid stimulating hormone; Chinese medicine therapy