Abstract
Objective:To investigate the clinical effect of fallopian tube obstruction recanalization by ozone.Methods:Total 116 cases of patients undergoing the fallopian tube obstruction were randomly divided into the experimental group and control group, with 58 cases in each group. All patients underwent the interventional fallopian tube recanalization. The patients in the experimental group underwent the fallopian tube perfusion by the ozone water. Meanwhile, the patients in the control group were treated with the conventional anti-inflammatory and anti-adhesion drugs. After the follow-up visit for 6 months, the pregnancy rate and fallopian tube re-occlusion rate were counted and compared between the two groups. Meanwhile, the symptoms were evaluated and compared between the two groups after the operation for two weeks.Results:The success rate of fallopian tube recanalization was 93.1% (54/58), the pregnancy rate was 79.3% (46/58) and the recurrence rate was 5.2% (3/58) in the experimental group. While the success rate of fallopian tube recanalization was 91.4% (53/58), the pregnancy rate was 60.3% (35/58) and the recurrence rate was 17.2% (10/58) in the control group. Analysis showed that there was no significant difference in the recanalization success rate between the two groups (P>0.05). However, the pregnancy rate and re-occlusion rate in the experimental group were significantly lower than those of the control group (P<0.05), and the difference was statistically significant. There was no significant difference in the discomfort symptoms between the experimental group and control group (P>0.05).Conclusion:Fallopian tube recanalization by ozone perfusion can effectively increase the postoperative pregnancy rate and reduce the fallopian tube re-occlusion.
Highlights
Fallopian tube factor is one of the most common causes of infertility.[1]
The therapeutic effect of operation: The success rate of fallopian tube recanalization was 93.1% (54/58) in the experimental group, while the control group was 91.4% (53/58)
The analysis showed that the pregnancy rate and re-occlusion rate in the experimental group were significantly lower than those of the control group (P
Summary
Fallopian tube factor is one of the most common causes of infertility.[1] For the multipara, the fallopian tube adhesion and obstruction induced. Correspondence: November 23, 2016 December 5, 2016 February 9, 2017 February 15, 2017 by the tubal, uterine and pelvic inflammation are relatively common. Inflammatory stimulation can cause the fallopian tube wall stiffness, peripheral tissue adhesion and lumen obstruction, so that it is difficult to pick up the ovum and delivery the sperm, and inducing the secondary infertility.[2]. In order to adjust the population policy in China, the full liberalization of the second child policy was formally implemented in January 1st 2016, which means that a couple can give birth to two babies. The multipara has strong desires of childbearing again. How to effectively recanalize the obstructed fallopian tube becomes an important clinical problem for the pregnancy again.
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