Clinical observation of BiPAP noninvasive ventilation in the treatment of acute cardiogenic pulmonary edema

Abstract

Objective To investigate the clinical value of Bi - level positive airway pressure( Bi-PAP) noninvasive ventilation on acute cardiogeni(c) pulmonary edema. Methods Eighty patients with a cute cardiogenic pulmonary edema were randomly divided into two groups: treatment group and control group. Forty patients in the treatment group were treated with noninvasive mask Bi -level positive airway pressure (BiPAP) ventilation in addition to conventional treatment. Forty patients in the control group were treated by nasal pipe with oxygen in addition to conventional treatment. Patients were observed before and after the clinical symptoms,signs and arterial blood gas analysis. Results After BiPAP ventilation,the clinical symptoms of 37 patients in the treatment group had been improved significantly in two hours.Also, the clinical symptoms and arterial blood gas parameters ( pH, PaO2, PaCO2, SaO2 ) showed a statistical differences ( P <0. 05 ) compared with control group. The total efficiency rate of treatment group was 92.5% ,while that of control group was only 57.5%. Conclusions Bi - level positive airway pressure therapy is effictive and safe in acute pulmonary edema. Key words: Acute cardiogenic pulmonary edema; Bilevel positive airway pressure; Noninvasive ventilation