Abstract

Objective To explore the new therapeutic strategy of repairing large area of skin and soft tissue defect accompanied with severe trauma and/or major burn or other injuries. Methods Twelve trauma patients with large area of skin and soft tissue defect who were admitted to our hospital during December of 2007 to August of 2009 were enrolled in this trial for retrospective study. The style of management was evaluated in these patients. Artificial dermal (Pelnac) was grafted onto the wound granulation tissue after the primary debridement. The scalp autoskin (blade-thick) was grafted onto the surface of the Pelnac after the removing of its silicon membrane during the secondary operation. Results The wound healed completely with the survival of skin grafting and satisfactory appearance in all 12 patients.Furthermore, the scar in the donor site exhibited unconspicuous. Conclusion It' s an optimal choice to repair large skin and soft tissue defect with Pelnac and scalp autoskin(blade-thick). Key words: Pelnac; Blade-thick autoskin; Large area skin and soft tissue defect; Compound grafting

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