Clinical observation for central serous chorioretinopathy by laser treatment and drug therapy

Abstract

Objective To compare the efficacy of central serous chorioretinopathy by laser treatment and drug therapy. Methods Selected 69 outpatient with central serous chorioretinopathy (CSC) confirmed by imaging FFA were randomly divided into three groups: laser treatment group, 21 eyes, promoting blood circulation treatment group 23, and support therapy group 23. Omni multi-wavelength laser with krypton laser, promoting blood circulation by Fufang XueShuanTong capsule, supportive therapy with co-VitB, inosine, ATP.Comparative analysis of the follow-up 3 weeks, 6 weeks of treatment effect and the average healing time, the final follow-up vision, x2 and t test to analyze statistical significance. Results (1) laser treatment group was followed up for 3 weeks and 6 weeks the cure rate was 66.7% and 100%, the average healing time (x± s) 2.81± 0.65w, the final follow-up visual acuity 1.08 ± 0.11. (2) follow-up promoting blood circulation group 3weeks and 6 weeks the cure rate was 26.0% and 47.8%, the average healing time was 7.23 ± 4.51w, the final follow-up visual acuity 0.98 ± 0.15. (3) supportive care group were followed up for 3 weeks and 6 weeks the cure rate was 16.0% and 34.8%, The average healing time 9.78 ± 6.86 w, the final follow-up visual acuity 1.05± 0.23. (4) Laser treatment group compared with the drugs treatment group, 3 weeks and 6 weeks the cure rate was P ＜0.01, the average healing time was P ＜0.01, the final follow-up visual acuity P＞ 0.05. (5) the recurrence rate after cure, the laser group 4.4%, 17.3% blood circulation group to support the therapy group 20%. Conclusions Comparison of drug therapy, laser therapy can increase cure rate of central serous chorioretinupathy,shorten healing time, reduce the relapse rate, but do not affect the final visual acuity. Key words: Central serous chorioretinopathy (CSC); Laser treatment