Abstract

PurposeMalnutrition is a common problem among pancreatic cancer (PC) patients that negatively impacts on their quality of life (QoL) and clinical outcomes. The main objective of this consensus is to address the role of Medical Nutrition Therapy (MNT) into the comprehensive therapeutic management of PC patients.MethodsA Spanish multidisciplinary group of specialists from the areas of Medical Oncology; Radiation Oncology; Endocrinology and Nutrition; and General Surgery agreed to assess the role of MNT as part of the best therapeutic management of PC patients.ResultsThe panel established different recommendations focused on nutritional screening and nutritional screening tools, MNT strategies according to PC status, and MNT in palliative treatment.ConclusionsThere is an unmet need to integrate nutritional therapy as a crucial part of the multimodal care process in PC patients. Health authorities, health care professionals, cancer patients, and their families should be aware of the relevance of nutritional status and MNT on clinical outcomes and QoL of PC patients.

Highlights

  • The annual incidence of pancreatic ductal adenocarcinoma (PC) has been increasing and, due to its poor prognosis, PC accounts for almost as many deaths as cases [1, 2]

  • Recommendation 1: nutritional screening should be performed in all PC patients, preferably by the specialist establishing the first diagnosis

  • Recommendation 2: pancreatic cancer patient nutritional status needs to be considered as a dynamic reality, which depends on multiple factors, and should be reassessed periodically during the different phases of disease treatment pathway

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Summary

Introduction

The annual incidence of pancreatic ductal adenocarcinoma (PC) has been increasing and, due to its poor prognosis, PC accounts for almost as many deaths as cases [1, 2]. Pancreatic cancer remains one of the cancers with the poorest prognosis, with an overall 5-year survival rate of about 5% [4, 5]. The impact of recent improvements in both medical and surgical treatments on 5-year survival rates has. Pancreatic cancer is often diagnosed late, with only approximately 20% of patients having surgically resectable tumor at the time of diagnosis [6, 7]. Three quarters of them recur after surgery and 5-year survival is approximately 27%, while those with locally advanced or metastatic cancer have a median survival ranging from 6 to 11 months [5]

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