Abstract

Background: Neurological detrusor overactivity (NDO) is commonly associated with various neurogenic diseases. Botulinum toxin A (BTX-A) has been proposed as alternatives to traditional treatments. Objective: To summarize the clinical experience of nursing care for the treatment of the Botulinum toxin A (BTX-A) injections due to neurological detrusor overactivity (NDO). Methods: We reviewed the data of 32 inpatients who received BTX-A injections between August 2014 to July 2016. Their mean age was 27.4 years old (range: 19 - 38). They were all on clean intermittent catheterization. All patients presented detrusor overactivity resistant to oral anticholinergic treatment. Results: There were significant difference between outcomes at baseline and week12 for Pdetmax (60.08 cmH2O vs. 28.04 cmH2O, P < 0.001), VFIDC (165.55 ml vs. 276.07, P < 0.001), and urinary incontinence respectively. Prompt psychological counseling and nursing help reduce the patients’ passive psychology, enhance their confidence with good postoperative recovery and symptoms improvement. Conclusions: Patients were satisfied with the treatment and nursing by targeted perioperative nursing.

Highlights

  • Patients were satisfied with the treatment and nursing by targeted perioperative nursing

  • Neurological detrusor overactivity (NDO) is characterized by spontaneous or provoked involuntary detrusor contractions during storage phase in urodynamic investigation which caused by various neurogenic diseases such as Parkinson’s disease, stroke and spinal cord injury [1] [2]

  • Botulinum toxin A (BTX-A) is a neuromuscular blocking agent indicated by the beneficial treatment effect on NDO patients who have an inadequate response to or are intolerant to anticholinergic medication [4]

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Summary

Introduction

Neurological detrusor overactivity (NDO) is characterized by spontaneous or provoked involuntary detrusor contractions during storage phase in urodynamic investigation which caused by various neurogenic diseases such as Parkinson’s disease, stroke and spinal cord injury [1] [2]. Botulinum toxin A (BTX-A) is a neuromuscular blocking agent indicated by the beneficial treatment effect on NDO patients who have an inadequate response to or are intolerant to anticholinergic medication [4]. Encouraged by our satisfactory clinical effects, we summarized our perioperative nursing experience for BTX-A injection. Objective: To summarize the clinical experience of nursing care for the treatment of the Botulinum toxin A (BTX-A) injections due to neurological detrusor overactivity (NDO). Methods: We reviewed the data of 32 inpatients who received BTX-A injections between August 2014 to July 2016. Their mean age was 27.4 years old (range: 19 - 38). Conclusions: Patients were satisfied with the treatment and nursing by targeted perioperative nursing

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