Abstract
Celiac disease is characterized by significant clinical polymorphism, which makes it difficult to diagnose and postpones the start of pathogenetic treatment, ultimately worsening the prognosis of the disease. In this regard, knowledge of the clinical features and variants of the disease is of paramount importance for an effective diagnostic process. The article discusses various options for the clinical manifestations of celiac disease. The possibility of celiac disease should be borne in mind in patients with: 1. a history and clinical manifestations characteristic of celiac disease; 2. symptoms of celiac disease associated diseases; 3. symptoms that may be a manifestation of atypical celiac disease. Relatives of celiac patients are also at risk. Overweight and constipation do not reject the diagnosis of celiac disease. Taking into account all these circumstances will make it possible to diagnose and begin treatment in a timely manner, reasonably counting on its maximum effectiveness
Highlights
С другой стороны, манифестацию целиакии часто принимают за другие заболевания, что становится причиной диагностических ошибок [5]
Как правило, хороший эффект безглютеновой диеты почти во всех случаях заболевания, включая впервые возникшие после кишечной инфекции» [11]
Prevalence and clinical picture of celiac disease in Italian Down syndrome patients: a multicenter study
Summary
Celiac disease is characterized by significant clinical polymorphism, which makes it difficult to diagnose and postpones the start of pathogenetic treatment, worsening the prognosis of the disease. In this regard, knowledge of the clinical features and variants of the disease is of paramount importance for an effective diagnostic process. The article discusses various options for the clinical manifestations of celiac disease. A history and clinical manifestations characteristic of celiac disease; 2. Symptoms that may be a manifestation of atypical celiac disease. Такое развитие событий обычно рассматривается как «типичная» целиакия, однако на практике часто встречается «атипичное» течение, при которой на первый план выходят внекишечные проявления заболевания
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