Clinical Manifestations and Outcomes of Respiratory Syncytial Virus Infection in Children Less Than Two Years in Colombia

Abstract

This retrospective study describes the epidemiology and risk factors associated with severe complications in lower respiratory tract infection (LRTI) due to respiratory syncytial virus (RSV) in a population of infants hospitalized in a tertiary care hospital in a tropical region of Colombia. RSV was detected in 193 (46.3%) of 417 patients with LRTI. The average hospital stay lasted for 5.9 days. Severe hypoxemia (SpO2 ≤90% in the emergency department) was present in 57.5% of the patients. After controlling for potential confounders, comorbidities bronchopulmonary dysplasia, congenital heart disease, length of hospital stay, and alveolar infiltrates in X-ray were independent predictors of severe complications in RSV LRTI.