Clinical Manifestations and Comorbidities of SARS-Cov-2 Infection: A Descriptive Study

Abstract

Background: Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe illness have an overactive immune system, which can damage organs other than the lungs. Objective: The aim of this study was to assess the prevalence of clinical manifestations and comorbidities in SARSCoV- 2 infected patients. Patients and methods: This retrospective single-center observational study was conducted in the Tertiary Hospital, Internal Medicine Department, Faculty of Medicine, Zagazig University. This retrospective observational study was conducted on consecutive 370 patients with confirmed SARS-CoV-2 infection from May to September 2020.The diagnosis of the cases was confirmed using RT-PCR for detection of the viral RNA. Demographic characteristics, including underlying comorbidities, symptoms, signs, laboratory findings, chest CT scan and treatment measures were reported. Results: According to this retrospective, single-center observational study, which was conducted on consecutive 370 patients with confirmed SARS-CoV-2 infection? The study involved 193 Egyptian males (52.1%) and 177 Egyptian females (47.9%) with COVID-19. The mean age was 40. 2 ±14.74 years. The common symptoms of the COVID-19 patients at the onset of sickness were myalgia [355 (95.9%)], fatigue [291 (78.6%)], headache [235 (63.5%)], fever [247 (66.8%)], cough [213 (57.6.%)], sputum production [201 (54.3%)] and dyspnea [189 (51.1%)].The most prevalent comorbidity were hypertension [142(38.4%)] followed by diabetes [132 (35.6%)]. Conclusion: The commonest clinical manifestations of confirmed cases of COVID-19 were myalgia, fatigue, headache, fever, and cough and the most prevalent comorbidities associated with COVID 19 patients were hypertension and diabetes. [ABSTRACT FROM AUTHOR] Copyright of Egyptian Journal of Hospital Medicine is the property of Egyptian Journal of Hospital Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)