Abstract
Ulcerative colitis is recurrent inflammatory disorder of the large intestine characterized by continuous expansion of bowel involvement, from the rectum to the proximal parts. Despite certain similar sign with adults, ulcerative colitis in children has a number of special features and distinctions to disease course and therapy response, therefore such peculiarities should be considered while choosing the management strategy. In 2012 European Crohn’s and Colitis Organisation and European Society for Pediatric Gastroenterology, Hepatology and Nutrition developed collaborated recommendations on diagnostics and treatment of ulcerative colitis in children based on the evidence-based medicine. On the base of European recommendations and with regard to Russian peculiarities and experience of management of children with ulcerative colitis the Russian Consensus on Ulcerative Colitis in children was developed by the group of the chief pediatric gastroenterologists specializing in inflammatory bowel diseases in children. This Consensus was approved on the 15 th of February 2013 at the Expert Counsel on Development of the Russian Consensus, which took place during the XVII Summit of Pediatricians of Russia. These recommendations contain standardized protocols, which allow to provide timely and efficient diagnostics, treatment and follow-up of children with ulcerative colitis. It is necessary to mention, that this Consensus is not a doctrine and individual features of each patient and modern scientifically based data must be taken into account.
Highlights
Российская Федерация 7 Самарский государственный медицинский университет, Российская Федерация 7 Ярославская государственная медицинская академия, Российская Федерация 8 Московский областной научно-исследовательский клинический институт им
Инфликсимаб (Ремикейд) следует назначить при горриод до 10–14 нед от начала лечения
Суммарный индекс PUCAI составляет 0–85 [71]
Summary
18 Клиническая картина, диагностика и лечение язвенного колита у детей: Российский педиатрический консенсус. Несмотря на имеющиеся сходные признаки с таковым у взрослых больных, имеет ряд особенностей и отличий по характеру течения и ответу на терапию, в связи с чем в подходах к ведению детей нужно также учитывать эти особенности. Ключевые слова: язвенный колит, дети, клинические рекомендации, диагностика и лечение, педиатрический индекс активности язвенного колита. Гормональная зависимость констатируется при достижении клинической ремиссии на фоне терапии ГК и возобновлении симптомов при снижении дозы или в течении 3 мес после полной отмены, а также в случаях, если терапию стероидами не удается прекратить в течение 14–16 нед.
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