Abstract
Alcoholism-associated liver disease is a potentially preventable hepatic injury. By use of 25 routinely ordered clinical laboratory tests, alcoholic cirrhosis was distinguishable from noncirrhotic alcoholic liver disease in 53 male inpatients with biopsy-verified liver disease (31 diagnosed with alcoholic cirrhosis and 22 diagnosed with fatty liver and/or alcoholic hepatitis). Linear discriminant analysis correctly classified 77% of subjects with cirrhotic liver disease and 68% of subjects with noncirrhotic liver disease (overall accuracy of 74%). Quadratic discriminant analysis correctly classified 94% of subjects with cirrhotic liver disease and 68% of subjects with noncirrhotic liver disease (81% overall accuracy). These pattern recognition techniques may allow earlier clinical intervention in alcoholic patients with liver disease.
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