Clinical Investigation on the Relationship between Upper Urinary Tract Obstruction and the Accompanied Chronic Cystitis

Abstract

Objective: To explore the relationship between upper urinary tract obstruction and the accompanied chronic cystitis. Patients and Methods: The prospective study was carried out in 350 patients with upper urinary tract obstruction. They were inspected by urinary bacterial culture, cystoscopy and ureteroscopcy. Results: In 350 cases of upper urinary tract obstruction, 75 (21.45%) cases were accompanied with visible chronic cystitis. Fifty-one (20.08%) cases were accompanied with chronic cystitis in 254 cases of upper urinary tract obstruction induced by renal and ureteral stone, and 24 (25.00%) cases were accompanied with chronic cystitis in 96 cases by other factors (p > 0.05). Fifty-eight of 350 (16.57%) cases were chronic nonbacterial cystitis in 75 cases of chronic cystitis. Among them, 38 (10.86%) cases were cystitis glandularis, 11 (3.14%) cases were vesical leukoplakia and 9 (2.57%) cases were chronic hyperplastic cystitis. Six (10.34%) cases were positive urine culture in 58 cases of accompanied chronic nonbacterial cystitis in upper urinary tract obstruction, and 27 (9.82%) cases were positive urine culture in 275 cases without cystitis, as compared between 2 groups (p > 0.05). Following up to 16 cases of accompanied chronic non-bacterial cystitis in upper urinary tract obstruction, the clinic symptom and suspicious inflammation foci on the bladder in 10 cases was disappeared, but that in 6 cases remained visible and needed further management. Conclusion: It is suggested that there would be an association of upper urinary tract obstruction with the accompanied chronic cystitis, and long-term upper urinary tract obstruction could induce chronic nonbacterial cystitis. The pathogenesis should be further studied.