Clinical investigation of cardiopulmonary function changes after pulmonary resection in old patients with lung tumor

Abstract

Objective To investigate the cardiopulmonary function in the old patients with lung tumor resection at rest and during maximum exercise by echocardiography. And provide more suitable operation-index for lung tumor. Methods A total of 41 patients with lung tumor who had undergone lung resection were divided into two groups: the elder patients group ( ≥60 years) containing 24 cases while the middle-younger patients group ( < 60 years) containing 17 cases. When they behaved themselves normally in their daily lives, the cardiopulmonary function were monitored by cardiopulmonary functional instrument and echocardiography from 3～5 days preoperatively and 3～6 months postoperatively. Heart rate ( HR) , left ventricular end - diastolic volume (LVEDV), stroke volume (SV) , cardiac output (CO), Left ventricular ejection fraction (LVEF), respiration rale (RR) , tidal volume (VT) , minute ventilation (VE) , and oxygen consumption (VO(2) ) were observed and analyzed. Results Levels of LVEDV and SV were decreased after operation both at rest and undermovement (P<0.01). The were statistical significance of HR, RR, VT at rest and RR, VT, VE, VO(2), CO during movement before and after operation (P<0. 05 or P<0.01). After being divided into two groups, SV and VT afteroperation were decreased in both groups at restwhile. CO, VE and VO(2) showed statistical siginificance before and after operation. VO(2) was decreased in both groups postoperatively undermovement. VE was decreased in the elder patients group. Conclusions At rest, contents of CO and VE after operation were preserved by the increment of HR and RR, the decrement of CO and VE were not compensated by HR and RR. In older patients group, postoperative decrease of VO(2) was mainly due to VE decreasing while inmiddle-younger patients group, it was due to CO lowering. Key words: Lung tumor; Pneumonectomy; Heart function; Lung function