Abstract
Introduction: Gastric cancer is a disease with a high rate of morbidity and mortality in the world. Objective: To determine which clinical inflammatory biomarkers are associated with the tumor stage of gastric cancer of the oncology service of the Hospital María Auxiliadora in Lima, Peru, during the years 2018-2020. Methodology: Observational, analytical, cross-sectional and retrospective study. There was a sample of 110 patients. The PR values were obtained from the absolute frequencies of the variables: serum albumin, Platelet-Lymphocyte Ratio (PLR) and Neutrophil-Lymphocyte Ratio (NLR). Results: The average age was 63,727±13.85. 55.45% were female. The most frequent histopathological type was intestinal adenocarcinoma with 62.73%. In the bivariate analysis, an association was found between INL (PR:6.88 CI95% 2.36-20 p<0.001), IPL (PR:2.55 CI95% 1.68-3.86 p<0.001) and serum albumin (PR:3.16 CI95% 1.91-5.24 p<0.001) in the advanced clinical stage. The multivariate analysis found a relationship between INL and clinical stage (PR:4.11 CI95% 1.25-13.49 p=0.020) Conclusion: INL is an independent predictive factor in relation to the clinical stage of gastric cancer in this study.
Highlights
Gastric cancer is a disease with a high rate of morbidity and mortality in the world
This study seeks to determine the clinical factors associated with tumor stage in gastric cancer that are of easy access and low cost, in order for them to help us identify survival and an adequate treatment
Our objective was to determine the clinical-inflammatory factors associated with tumor stage of gastric cancer of the oncology service of Hospital María Auxiliadora during the years 2018–2020
Summary
Gastric cancer is a disease with a high rate of morbidity and mortality in the world. Objective: To determine which clinical inflammatory biomarkers are associated with the tumor stage of gastric cancer of the oncology service of the Hospital María Auxiliadora in Lima, Peru, during the years 2018-2020. The prognostic molecular, genomic factors and other high complex instruments are currently not available in all hospital centers in economically emerging countries. For this reason, this study seeks to determine the clinical factors associated with tumor stage in gastric cancer that are of easy access and low cost, in order for them to help us identify survival and an adequate treatment
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