Abstract
Onboard cone beam CT (CBCT) allows one to acquire volumetric anatomical information of a patient prior to treatment on a routine basis and makes it possible to adaptively modify the patient treatment plan with consideration of organ deformation as well as previously delivered doses. The aim of this work is to develop a clinically practical offline and eventually online adaptive therapy procedure and evaluate the potential impact of the CBCT-based adaptive head and neck IMRT treatment.
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