Abstract

Objective: To investigate the clinical, laboratory, and radiological characteristics of patients with coronavirus disease-2019 (COVID-19) in Heilongjiang Province.Results: Patients in the ICU group were older and their incidence of cardiovascular disease was higher than those in the non-ICU group. Lymphocyte levels were lower and neutrophil and D-dimer levels were higher in the ICU than that in the non-ICU group. Compared to the non-ICU group, the incidence of pulmonary consolidation and ground-glass opacity with consolidation was significantly higher in the ICU group, all lung lobes were more likely to be involved, with higher number of lung lobes and areas surrounding the bronchi. Of the 59 patients with COVID-19 in this group, 15 received mechanical ventilation. All intubated patients involved lung lobes, and a large number of lesions were observed in the area around the bronchial vessels.Conclusion: Significant differences were observed in clinical symptoms, laboratory tests, and computed tomography features between the ICU and non-ICU groups.Methods: A total of 59 patients with COVID-19, comprising 44 patients in the intensive care unit (ICU) and 15 in the non-ICU, were retrospectively analyzed. Characteristics of the two groups of patients were compared.

Highlights

  • An outbreak of new pneumonia caused by the 2019 novel coronavirus (2019-nCoV) started in Wuhan, China, in December 2019 [1]

  • The COVID-19 pandemic has caused severe illness in infected patients, such as pneumonia and acute respiratory distress syndrome, which even resulted in death

  • This study describes the clinical and radiological characteristics and laboratory examination data of 59 patients with COVID-19 and compares between those admitted in the intensive care unit (ICU) and non-ICU departments

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Summary

Introduction

An outbreak of new pneumonia caused by the 2019 novel coronavirus (2019-nCoV) started in Wuhan, China, in December 2019 [1]. In January 2020, Chinese scientists isolated this 2019-nCoV from patients with viral pneumonia, officially naming it as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]. The COVID-19 pandemic has caused severe illness in infected patients, such as pneumonia and acute respiratory distress syndrome, which even resulted in death. Clinicians and radiologists should identify the characteristic imaging manifestations in chest CT findings of critically ill individuals, so that they can perform specific symptomatic treatment at the earliest, prevent complications, and provide organ functional support. A few reports demonstrated the clinical imaging features of severe and critically ill patients during the epidemic in Heilongjiang Province. We hope that these current results could be used by clinicians in Heilongjiang Province and worldwide for the treatment plan of COVID-19

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