Abstract
The vertebrabasilar (VB) system plays an essential role in the circulation of main structures of nervous system. As a part of Circle of Willis, it is responsible for major compensatory abilities of brain circulation in some hemodynamic disorders. On the other hand, some pathological diseases, involving VB system, could be fatal or could lead to severe injuries and functional wastes in the patient. Many variations and anomalies in VB system are common cause of hemodynamic disorders and vascular disease such as atherosclerosis. The good knowledge of variations and anatomy as well, allows us to understand pathophysiology and pathogenesis in those disorders, which in combination with specific clinical symptoms, helps us in making the fast and accurate diagnosis. This is fundamental for starting proper treatment.
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