Abstract

Introduction: Epstein-Barr virus (EBV) infection most commonly manifests as acute infectious mononucleosis but is usually asymptomatic. Objective: To describe the clinical features, pathological findings and outcome of children admitted to a tertiary care paediatric hospital with EBV infection. Method: The study group included children who were admitted with various presentations of EBV such as dengue like illness, prolonged fever, myocarditis, encephalitis and haemophagocytic lymphohistiocytosis (HLH) over the last 3 years. Results: In our study, 16 (45.7%) children had a dengue like illness, 5 (14.3%) had myocarditis, 1 (2.9%) had HLH, 2 (5.7%) had encephalitis and 11 (31.4%) had prolonged fever. Conclusions: Dengue like illness and prolonged fever were the 2 most frequent presentations of EBV infection. Sri Lanka Journal of Child Health , 2017; 46 (3): 243-247

Highlights

  • Epstein-Barr virus (EBV) infection most commonly manifests as acute infectious mononucleosis but is usually asymptomatic

  • The study group included children who were admitted to the Chittaranjan Seva Sadan hospital, a tertiary care paediatric hospital in India, with various presentations of EBV such as dengue like illness, prolonged fever (>7 days), myocarditis, encephalitis and haemophagocytic lymphohistiocytosis over the last 3 years

  • We suspected EBV infection in the following categories of patients: Results: In our study, 16 (45.7%) children had a dengue like illness, 5 (14.3%) had myocarditis, 1 (2.9%) had HLH, 2 (5.7%) had encephalitis and 11 (31.4%) had prolonged fever

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Summary

Objective

To describe the clinical features, pathological findings and outcome of children admitted to a tertiary care paediatric hospital with EBV infection. Method: The study group included children who were admitted with various presentations of EBV such as dengue like illness, prolonged fever, myocarditis, encephalitis and haemophagocytic lymphohistiocytosis (HLH) over the last 3 years

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