Abstract

We examined pathogenesis and clinical features of three hemichorea-hemiballism (HCHB) cases. We studied their age, magnetic resonance imaging results, vascular risk factors, management, and outcomes. One man and two women (aged 74-86 years) demonstrated acute onset of HCHB, lasting for at least several months. Patients had one or more vascular risk factors, including hypertension and diabetes. All patients presented subacute or old infarction in the basal ganglia with contralateral symptoms. We administered clonazepam (0.5-1 mg/day), haloperidol (0.375-0.75 mg/day), or both as necessary and observed symptom-control. Vascular lesions in the basal ganglia were a contributing factor. Symptoms were controlled using pharmacotherapy with gamma-aminobutyric acid-agonist (clonazepam) or anti-dopaminergic (haloperidol) medication.

Highlights

  • An 81-year-old woman suddenly presented with continuous hemiballism/ choreic movements on her left arm and leg for one week before visiting our clinic

  • Chorea presents as a condition that causes rapid, irregular, and involuntary movement that typically involves both proximal and distal muscles.[1,2] n Case Report #1 o Abstract se We examined pathogenesis and clinical u features of three hemichorea-hemiballism (HCHB) cases

  • Due to the severity of daily life disruptions caused by HCHB, which lasted at least several months in one case, we treated them with clonazepam (0.5-1 mg/day), haloperidol (0.375-0.75 mg/day), or both as necessary to control the observed ly symptoms

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Summary

Introduction

An 81-year-old woman suddenly presented with continuous hemiballism/ choreic movements on her left arm and leg for one week before visiting our clinic. Chorea presents as a condition that causes rapid, irregular, and involuntary movement that typically involves both proximal and distal muscles.[1,2] n Case Report #1 o Abstract se We examined pathogenesis and clinical u features of three hemichorea-hemiballism (HCHB) cases. All patients presented subacute or old m infarction in the basal ganglia with o contralateral symptoms.

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