Clinical features of children with lobar pneumonia caused by mycoplasma pneumoniae infection

Abstract

Objective To investigate clinical features of mycoplasma pneumoniae pneumonia (MPP) of the lobar pneumonia, to help early recognition, diagnosis and treatment. Methods 173 children diagnosed as lobar pneumonia in the inpatient department from October 2014 to October 2016 were divided into 115 cases of lobar pneumonia caused by mycoplasma pneumonia (MP) infection and 58 cases of lobar pneumonia caused by non-MP infection. Compared and analyzed the clinical symptoms, imageology, and inflammation indexes respectively. Results There were 55 male cases and 60 female cases in MP group, there were 34 male cases and 24 female cases in non-MP group, without statistically significant difference between the two groups (P>0.05). There were 15 cases under 3 years old and 100 cases over 3 years old in MP group, there were 22 cases under 3 years old and 36 cases over 3 years old in non-MP group, with statistically significant difference between the two groups (P 0.05); there was statistically significant difference in extrapulmonary manifestation (P<0.05), the rate of myocardial damage in non-MP group was significantly higher than that in MP group. In terms of imageology, the rate of involving in 2 or more lobes in non-MP group was significantly higher than that in MP group (P<0.01). The level of C-reactive protein (CRP) in non-MP group was significantly higher than that in MP group (P<0.05), there were no statistically significant differences in the levels of peripheral white blood cell (WBC) and serum procalcitonin (PCT) between the two groups. After systemic treatment, 99.4% (172 cases) of the children had good prognosis, and 1 case was transferred to the superior hospital. Conclusions In the early stage of lobar pneumonia which MP-IgM antibody titer is not increased, the age, extrapulmonary manifestation, imageology differences, and serum CRP are helpful to early definite diagnosis of MP infection lobar pneumonia and non-MP infection lobar pneumonia, and reasonable and timely treatment, to improve the prognosis of children. Key words: Lobar pneumonia; Mycoplasma pneumonia; Children