Clinical features and pathogens analysis of complicated and non-complicated urinary tract infections in infants

Abstract

Objective To summarize the clinical and pathogenic characteristics of urinary tract infection(UTI) in infants, and to provide reference for clinical diagnosis and treatment. Methods One hundred and eighty-eight cases of hospitalized infants with UTI diagnosis standard in Department of Pediatric Renal Rheumatism Immunology, Shengjing Hospital Affiliated to China Medical University from January 2012 to January 2015 were collected, and on the basis of the imaging they were divided into complex group(complicated UTIs) and non-complex group(non-complicated UTIs), the differences between 2 groups in the general condition, clinical manifestations, serological examination, urine culture and distribution of pathogenic bacteria and drug sensitivity results were analyzed. Results Among 188 UTI infants, 148 were male and 40 were female, 50 cases were in complex group(26.6%), and 138 cases were in non-complex group(73.4%). In complex group, the prevalence of prenatal ultrasound abnormalities(34.0%), the incidence of recurrent infections(24.0%), the number of fever incidence(78.0%), and peripheral WBC count[(16.4±4.3)×109/L] were higher than those in non-complex group[1.5%, 10.9%, 58.7%, (14.6±3.5)×109/L](all P<0.05), and the naked eye hematuria incidence was lower than that of the non-complex group(14.0% vs 34.8%, P=0.006). In complex group, pneumonia klebsiella bacteria positive rate was higher than that of non-complex group(22.0% vs 2.9%, P=0.000), and the positive rate of Escherichia coli was lower than that of non-complex group(26.0% vs 46.4%, P=0.000). There was no difference in the drug sensitivity and resistance of the pathogenic bacteria in the urine culture of 2 groups. Conclusions For fever, increased peripheral WBC, repeated infection and urine culture for Klebsiella pneumoniae UTI infants, in particular, should be alert to the prese-nce of urinary tract abnormalities, timely improve the urinary system ultrasound and urinary tract contrast is very necessary. Key words: Infant; Urinary tract infection; Clinical feature; Pathogenic bacteria