Clinical features and neuroimaging analysis of hemichorea and non-ketotic hyperglycemia

Abstract

Three cases of nonketotic hyperglycemia plus hemichorea were treated from 2011 to 2012. And the clinical data, radiological diagnosis and treatment were retrospectively analyzed. Three patients were all elderly diabetics with an onset level of glucose> 20 mmol/L and negative urine ketone. Dance symptoms involved unilateral extremity and/or face. Cranial computed tomography showed high-density lesions in contralateral putamen and caudate nucleus head. And magnetic resonance imaging detected T1WI high signal, T2WI slightly low or equal signals. The diagnosis was based on clinical features and imaging manifestations. The primary treatment was lowering blood sugar plus uses of haloperidol, chlorpromazine and other drugs when necessary. Three cases were all cured. Key words: Hyperglycemia, nonketotic; Chorea; Diagnostic imaging