Abstract

Objectives: To study the signs and symptoms of neonatal sepsis caused by Klebsiella pneumoniae and the antibiotic sensitivity pattern of Klebsiella pneumoniae in a level 2 neonatal unit in India. Method : This descriptive study was conducted with neonates who were admitted in Sick Newborn Care Unit (level 2 neonatal care unit) and whose blood culture showed growth of Klebsiella pneumoniae in a study period of 1 year. The data was entered into a register and presented by descriptive statistics. Results: Forty eight neonates were included in the study. Predominant presenting symptoms were abdominal distension (75%), petechiae, purpura (62.5%) and sclerema (50%). Klebsiella pneumoniae was highly sensitive to tigecycline and meropenem. Conclusions: Predominant presenting symptoms of neonatal sepsis caused by Klebsiella pneumoniae were abdominal distension, petechiae, purpura and early sclerema. Klebsiella pneumoniae was highly sensitive to tigecycline and meropenem. Sri Lanka Journal of Child Health , 2017; 46 (3): 259-261

Highlights

  • Blood stream infection by multi-drug resistant gram-negative bacilli is one of the most worrisome challenges in the field of health care especially in intensive care units. Their impact is mostly felt in neonatal care units

  • Setting: Study was conducted at Sick Newborn Care Unit of College of Medicine and JNM Hospital, Kalyani, India

  • Participants: Subjects of the study were neonates who were admitted in sick newborn care unit and whose blood cultures showed growth of Klebsiella pneumoniae

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Summary

Introduction

Blood stream infection by multi-drug resistant gram-negative bacilli is one of the most worrisome challenges in the field of health care especially in intensive care units. License be the most common cause of nosocomial infection among all Gram-negative bacteria[2]

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