Abstract
Objective: Liver cirrhosis is responsible for significant morbidity and mortality. This research aims to determine the clinical presentation, etiology and complications of patients with liver cirrhosis from a population living at a high altitude region in Peru. Materials and methods: A retrospective study of the clinical presentation and complications of liver cirrhosis was conducted. One hundred eight (108) medical records of patients with liver cirrhosis admitted to the Internal Medicine Service of the Hospital Nacional Ramiro Priale Priale, Huancayo,were evaluated between 2010 and 2012. Results: Patients’ mean age was 60.5 years (range: 12–82 years) and 62.9 % were males. The most common etiology was alcohol consumption (63 %), followed by chronic hepatitis B and C (7.4 % and 2.8 %, respectively). Fifty-eight point three percent (58.3 %) of the patients had a Child-Pugh class B score and 31.30 % of them had a Child-Pugh class C score. The most frequent clinical presentation was abdominal distension (87 %). The most common complications were ascites (56 %), hepatic encephalopathy (47.2 %) and hepatorenal syndrome (8.3 %). Conclusions: Alcoholic liver cirrhosis was the most common etiology. The most frequent complications were ascites and hepatic encephalopathy
Highlights
Liver cirrhosis is responsible for significant morbidity and mortality
etiology and complications of patients with liver cirrhosis from a population living at a high altitude region in Peru
medical records of patients with liver cirrhosis admitted to the Internal Medicine Service of the Hospital Nacional Ramiro Prialé Prialé
Summary
Características clínicas y complicaciones de la cirrosis hepática en una población de altura (Huancayo, 3250 m s. n. m.). Características clínicas y complicaciones de la cirrosis hepática en una población de altura Esta investigación trata de determinar la presentación clínica, la etiología y las complicaciones de los pacientes con cirrosis hepática en una población que habita en una región de altura del Perú. Materiales y métodos: Evaluación retrospectiva de la presentación clínica y las complicaciones de la cirrosis hepática. La etiología más frecuente fue la ingesta alcohólica (63,00 %) seguida por las hepatitis B y C crónicas (7,40 % y 2,80 %, respectivamente). Las complicaciones más comunes fueron la ascitis (56,00 %), la encefalopatía hepática (47,20 %) y el síndrome hepatorrenal (8,30 %). Conclusiones: La cirrosis alcohólica fue la etiología más común y las complicaciones más frecuentes fueron la ascitis y la encefalopatía hepática. Clinical features and complications of liver cirrhosis in a high-altitude population (Huancayo, 3,250 m a.s.l.)
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