Abstract

(Abstracted from Ultrasound Obstet Gynecol 2022;59:33–39) First described in 1997, the presence of cell-free fetal DNA in maternal plasma has been increasingly used in the last decade for cell-free DNA (cfDNA)–based noninvasive prenatal testing (NIPT) thanks to advances in molecular genetic technology. This method, now commonly used in the detection of fetal chromosomal abnormalities, can test for a variety of conditions.

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