Clinical Evaluation of Three Different Daily Disposable Soft Contact Lens Materials

Abstract

Purpose: To compare the subjective symptoms, objective signs and tear film of three different daily disposable hydrogel contact lenses (DDCL). Methods: Thirty three(male:2, female:31; mean 21.94±1.58 years) subjects who have successfully experienced wearing soft contact lenses were refitted with three different DDCL [A (Nesofilcon A), B (Omafilcon A) and C (Etafilcon A)] randomly assigned to one of three DDCL with a subject-masked method. They were indicated to wear those DDCLs for more than 8 hours a day for two weeks, bilaterally. Assessments including contact lens fitting (centration, lag, push-up test), frequency and intensity of subjective symptoms, objective signs, and tear film test were evaluated and compared after wearing three different DDCLs. Results: The fitting of three different contact lenses were shown optimal, and A lens showed good centration, less movement in lag gaze and push-up test compared to other lenses(p<0.01). The frequency and intensity of the subjective symptoms were not statistically different between the lenses. There was significantly more conjunctival redness and staining observed in eyes wearing the A lens compared with other lenses(p<0.05), NIBUT (noninvasive break-up time) and TBUT (tear break-up time) were longer in eyes wearing the A lens than other lenses(p=0.000, p=0.008, respectively). Conclusion: Whereas subjective symptoms was not different, objective clinical symptoms and tear film stability were different after wearing three DDCLs. However, we could not find significant correlation between tear film, subjective and objective symptoms.