Clinical Evaluation of self and professionally applied desensitizing agents in relieving dentin hypersensitivity after a single topical application: A Randomized Controlled Trial.

Sr Samuel,Sg Khatri,S Acharya

doi:10.4317/jced.51439

Sr Samuel, Sg Khatri + Show 1 more

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https://doi.org/10.4317/jced.51439

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Abstract

Objectives: The objective of this study is to evaluate the efficacy of self and professionally applied desensitizing agents in relieving dentinal hypersensitivity after single direct topical application. Study Design: This was a randomized controlled trial conducted among 57 patients. 8% Arginine paste was self-applied by the subject and Gluma desensitizer was applied by investigator. Numeric rating scale was used to measure hypersensitivity after tactile stimulus, Schiff scale was used for cold and air blast stimuli respectively. Scores were recorded at baseline, immediately, 15 and 30 days after the application. Friedman, Wilcoxon test as post hoc was used to analyze within group differences, between group differences analyzed using Mann Whitney U test (P<0.05 considered significant). Results: 8% Arginine paste elicited significantly higher reductions in sensitivity (P<0.05) than that of Gluma group at all follow ups. There was a significant decrease in hypersensitivity for both the groups from baseline till final follow-up (P<0.05) for all three stimuli. 8% Arginine paste was found to be more effective than Gluma desensitizer in providing immediate relief from dentine hypersensitivity and also sustained the effect significantly for a period of 30 days. Conclusions: Self applied 8% Arginine paste is effective than professionally applied Gluma desensitizer in relieving dentinal hypersensitivity immediately and over a period of one month. Key words:Dentine hypersensitivity, arginine, gluma, desensitizing agents.

Highlights

Dentinal hypersensitivity [DH] is a common condition in daily practice, especially in patients who have abrasion, attrition, gingival recession and erosion of teeth
This paste has been introduced in a concentration of 8.0% for relieving DH by both self and professional application. The purpose of this double blind, randomized clinical trial was to evaluate the clinical efficacy of self-applied Colgate sensitive Pro-Relief [Colgate-Palmolive, Guildford, Surrey, UK], and professionally applied Gluma Desensitizer [Heraeus Kulzer, Armonk, NY, USA] in relieving the dentinal hypersensitivity after a single direct topical application over a period of one month
57 subjects with a mean age of 33.9 ±7.8 years were recruited in the study and five [9%] were lost to follow up [three subjects from Gluma group, two from Arginine], were excluded from the final analysis

Summary

Introduction

Dentinal hypersensitivity [DH] is a common condition in daily practice, especially in patients who have abrasion, attrition, gingival recession and erosion of teeth. Sealing the exposed dentinal tubules is restricted to in-office products like, HEMA-G [Hydroxyethyl Methacrylate and Glutaraldehyde], fluoride varnish, fluoride iontophoresis and lasers. These materials have been proved to provide relief from DH in one or more professional applications. The mechanism of action of Pro-arginine is that it mimics natural desensitizing process leading to spontaneous occlusion of open dentinal tubules by the formation of calcium and phosphate plugs [8]. This paste has been introduced in a concentration of 8.0% for relieving DH by both self and professional application. The purpose of this double blind, randomized clinical trial was to evaluate the clinical efficacy of self-applied Colgate sensitive Pro-Relief [Colgate-Palmolive, Guildford, Surrey, UK], and professionally applied Gluma Desensitizer [Heraeus Kulzer, Armonk, NY, USA] in relieving the dentinal hypersensitivity after a single direct topical application over a period of one month

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